Nature Unknown label
Credit hour 3
Total number of hours 29
Number of hours for lectures 15
Number of hours for tutorials 7
Number of hours for laboratory work 7

Prerequisites

Basics of molecular biology and genetics

Goals

NC

Content

Lectures (CM): 15hrs
• General introduction about epigenetics
• DNA methylation, RNA directed DNA methylation and regulation of transposable elements
• Histone variants and their chaperones
• Histone code and chromatin states
• The amaizing small RNA world
• Nuclear architecture and 3D genome organization
• Epigenomics and Breeding applications
• Comparative epigenomics in plants

Round table discussion (TD) 7.5hrs
Analysis of scientific publications
• DNA methylation, RNA directed DNA methylation and regulation of transposable elements
• Histone variants and their chaperones
• Histone code and chromatin states
• The amaizing small RNA world
• Nuclear architecture and 3D genome organization

Practical course (TP): 7.5hrs (to be discussed, can be converted into publication analysis)
• Analysis of DNA methylation in plant by Bisulfite-Seq (BS-Seq) and/or ChiP-Seq analysis. An example of dataset linked to one publication analysed with the students.

Additional Information

NC